| Editor's Comments |
| |
Article Title |
Author(s) |
Pages |
|
|
|
Editorial
The banks of the blue Danube are a beautiful setting to meet and review new and important issues. On the eve of the 38th annual meeting of the EASD, a symposium was held in the lovely and quaint city ...
|
Philip Raskin
|
1
|
|
|
|
Physiology and pathophysiology of KATP channels in the pancreas and cardiovascular system: A review
Abstract: KATP channels are present in pancreatic and extrapancreatic tissues such as heart and smooth muscle, and display diverse molecular composition. They contain two different structural subunits...
|
Susumu Seino
|
2-5
|
|
|
|
Effects of sulfonylureas on KATP channel-dependent vasodilation
Abstract: Introduction: Sulfonylureas are widely prescribed for the treatment of type 2 diabetes. Their therapeutic efficacy resides in the ability to bind to sulfonylurea receptors (SURs) present on ...
|
Fatima Z.G.A Cyrino,
Daniel A Bottino,
Flavio C Coelho,
Denis Ravel,
Eliete Bouskela
et al.
|
6-10
|
|
|
|
Differential selectivity of insulin secretagogues: Mechanisms, clinical implications, and drug interactions
Abstract: The sulphonylurea receptor (SUR) subunits of KATP channels are the targets for several classes of therapeutic drugs. Sulphonylureas close KATP channels in pancreatic β-cells and are used to ...
|
Fiona M Gribble,
Frank Reimann
|
11-15
|
|
|
|
Pathophysiological mechanisms of diabetic angiopathy
Abstract: The sequelae of chronic hyperglycemia in diabetes of all phenotypes are divided into microvascular and macrovascular complications. Microvascular disease causes blindness, renal failure, and...
|
Hans-Peter Hammes
|
16-19
|
|
|
|
Monocyte adhesion in diabetic angiopathy: Effects of free-radical scavenging
Abstract: Increased interaction of monocytes with vascular cells is linked to the development and progression of atherosclerosis in patients with diabetes. One major determinant of increased monocyte ...
|
Geneviève Renier,
Jean-Claude Mamputu,
Anne-Cécile Desfaits,
Omar Serri
|
20-29
|
|
|
|
Diabetic endothelial dysfunction: Effect of free radical scavenging in Type 2 diabetic patients
Abstract: Diabetes mellitus is characterized by oxidative stress, which in turn determines endothelial dysfunction. It has been recently demonstrated that gliclazide, a second-generation sulfonylurea ...
|
Giancarlo De Mattia,
O Laurenti,
D Fava
|
30-35
|
|
