Journal of Diabetes and Its Complications
Volume 25, Issue 3 , Pages 208-210 , May 2011

New onset type 1 diabetes presenting as ketoacidosis simultaneously presenting with autoimmune hyperthyroidism—a case report

  • Victoria Mercer

      Affiliations

    • Department of Medicine, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • ,
  • Verity Burt

      Affiliations

    • Department of Medicine, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • ,
  • Ketan K. Dhatariya

      Affiliations

    • Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • Corresponding Author InformationCorresponding author. Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK. Tel.: +44 1603 288170; fax: +44 1603 287320.

Received 24 November 2009 ,Revised 7 June 2010 ,Accepted 23 June 2010.

References 

  1. Baker JRJ. Autoimmune endocrine disease. Journal of the American Medical Association. 1997;278:1931–1937
  2. Battacharyya A, Wiles PG. Diabetic ketoacidosis precipitated by thyrotoxicosis. Postgraduate Medical Journal. 1999;75:291–292
  3. Bridgman JF, Pett S. Simultaneous presentation of thyrotoxic crisis and diabetic ketoacidosis. Postgraduate Medical Journal. 1980;56:354–355
  4. Gatling W, Budd S, Walters D, Mullee MA, Goddard JR, Hill RD. Evidence of an increasing prevalence of diagnosed diabetes mellitus in the Poole area from 1983 to 1996. Diabetic Medicine. 1998;15:1015–1021
  5. Lim D, Lunt H, Ojala R, Turner J. Simultaneous presentation of Type 1 diabetes and thyrotoxicosis as a medical emergency. New Zealand Medical Journal. 2004;117:U775
  6. Perros P, McCrimmon RJ, Shaw G, Frier BM. Frequency of thyroid dysfunction in diabetic patients: Value of annual screening. Diabetic Medicine. 1995;12:622–627
  7. Tunbridge WM, Evered DC, Hall R, Appleton D, Brewis M, Clark F, et al. The spectrum of thyroid disease in a community: The Whickham survey. Clinical Endocrinology. 1977;7:481–493
  8. Vaidya B, Pearce S. The emerging role of the CTLA-4 gene in autoimmune endocrinopathies. European Journal of Endocrinology. 2004;150:619–626
  9. Wu P. Thyroid disease and diabetes. Clinical Diabetes. 2000;18:38–40
  10. Yeo KF, Yang YS, Chen KS, Peng CH, Huang CN. Simultaneous presentation of thyrotoxicosis and diabetic ketoacidosis resulted in sudden cardiac arrest. Endocrine Journal. 2007;54:991–993

☆ We declare that we have no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

☆☆ Dr. Mercer and Dr. Burt drafted the initial versions of the manuscript. All three authors looked after the patient. Dr. Dhatariya was in charge of the patients' care and finalised the manuscript. He acts as the guarantor for this article.

PII: S1056-8727(10)00067-X

doi: 10.1016/j.jdiacomp.2010.06.002

Journal of Diabetes and Its Complications
Volume 25, Issue 3 , Pages 208-210 , May 2011

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