Journal of Diabetes and Its Complications
Volume 25, Issue 3 , Pages 208-210, May 2011

New onset type 1 diabetes presenting as ketoacidosis simultaneously presenting with autoimmune hyperthyroidism—a case report☆☆☆

  • Victoria Mercer

      Affiliations

    • Department of Medicine, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • ,
  • Verity Burt

      Affiliations

    • Department of Medicine, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • ,
  • Ketan K. Dhatariya

      Affiliations

    • Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK
    • Corresponding Author InformationCorresponding author. Elsie Bertram Diabetes Centre, Norfolk and Norwich University Hospital NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY Norfolk, UK. Tel.: +44 1603 288170; fax: +44 1603 287320.

Received 24 November 2009; received in revised form 7 June 2010; accepted 23 June 2010. published online 13 August 2010.

Abstract 

Autoimmune conditions are common with an estimated prevalence in the UK of 2.5%. The presence of one condition should always prompt the clinician to look for others if new symptoms arise. Autoimmune polyglandular syndromes are well described. However, it is unusual for two or more autoimmune conditions to present simultaneously. We describe a case of two autoimmune conditions—type 1 diabetes and Graves' disease—being diagnosed for the first time in the same individual at the same visit to the emergency department. We suggest that thyrotoxicosis be added to the list of potential precipitants for diabetic ketoacidosis.

Keywords: Ketoacidosis, Autoimmune hyperthyroidism

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☆ We declare that we have no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

☆☆ Dr. Mercer and Dr. Burt drafted the initial versions of the manuscript. All three authors looked after the patient. Dr. Dhatariya was in charge of the patients' care and finalised the manuscript. He acts as the guarantor for this article.

PII: S1056-8727(10)00067-X

doi:10.1016/j.jdiacomp.2010.06.002

Journal of Diabetes and Its Complications
Volume 25, Issue 3 , Pages 208-210, May 2011

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