Diabetic keto-acidosis as a presentation of cystic fibrosis-related diabetes: a case report☆☆☆
Abstract
Cystic fibrosis (CF) is one of the most common genetically inherited diseases and often complicated by diabetes mellitus. With increasing longevity, the incidence and prevalence of cystic fibrosis-related diabetes (CFRD) rise and microvascular complications develop. CFRD is an entity on its own with characteristics seen in both type 1 and type 2 diabetes. Keto-acidosis, a potentially life-threatening complication of diabetes, is an extremely rare presentation of CFRD.
Here we present the history of a 21-year-old CF patient with no prior diagnosis of CFRD who developed keto-acidosis after an episode of pulmonary infection.
Based on this case report we would like to emphasize the importance of screening for and early treatment of CFRD. We also discuss the management policy of CFRD and when and whether to initiate insulin therapy.
Keywords: Diabetic keto-acidosis, Cystic fibrosis-related diabetes, Pulmonary infection
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☆ Declaration of interest: there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.
☆☆ Funding: This paper did not receive any specific grant from any funding agency in the public, commercial, or non-for-profit sector.
PII: S1056-8727(10)00065-6
doi:10.1016/j.jdiacomp.2010.05.003
© 2011 Elsevier Inc. All rights reserved.
