Journal of Diabetes and Its Complications
Volume 25, Issue 2 , Pages 90-96 , March 2011

Stroke in the diabetic and non-diabetic population in Germany: relative and attributable risks, 2005–2007

  • Andrea Icks

      Affiliations

    • Department of Public Health, Center for Health and Society, Heinrich-Heine-University, Düsseldorf, Germany
    • Institute of Biometrics and Epidemiology, German Diabetes Center at the Heinrich-Heine-University, Leibniz-Center for Diabetes Research, Düsseldorf, Germany
    • Corresponding Author InformationCorresponding author. Department of Public Health, Center for Health and Society, Heinrich-Heine-University Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, Germany. Tel.: +49 211 81 1 9780; fax: +49 211 81 1 9778.
    • ,
  • Marsel Scheer

      Affiliations

    • Department of Public Health, Center for Health and Society, Heinrich-Heine-University, Düsseldorf, Germany
    • ,
  • Jutta Genz

      Affiliations

    • Department of Public Health, Center for Health and Society, Heinrich-Heine-University, Düsseldorf, Germany
    • ,
  • Guido Giani

      Affiliations

    • Department of Public Health, Center for Health and Society, Heinrich-Heine-University, Düsseldorf, Germany
    • ,
  • Gerd Glaeske

      Affiliations

    • University of Bremen, Centre for Social Policy Research, Bremen, Germany
    • ,
  • Falk Hoffmann

      Affiliations

    • University of Bremen, Centre for Social Policy Research, Bremen, Germany

Received 8 November 2009 ,Revised 17 May 2010 ,Accepted 28 May 2010.

References 

  1. Abbott RD, Donahue RP. Diabetes and the risk of stroke: The Honolulu Heart Program. JAMA. 1987;257:949–952
  2. Almdal T, Scharling H, Jensen JS, Vestergaard H. The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: A population-based study of 13,000 men and women with 20 years of follow-up. Archives of Internal Medicine. 2004;164:1422–1426
  3. American Diabetes Association . Standards of medical care for people with diabetes. Diabetes Care. 1998;21(S1):S21–S32
  4. Arnold-Wörner N, Holle R, Rathmann W, Mielck A. The importance of specialist treatment, treatment satisfaction, and diabetes education for the compliance of subjects with type 2 diabetes. Results from a population-based survey. Experimental and Clinical Endocrinology & Diabetes. 2008;116:123–128
  5. Barret-Connor E, Khaw KT. Diabetes mellitus: An independent risk factor for stroke?. American Journal of Epidemiology. 1988;128:116–123
  6. Bramesfeld A, Grobe TG, Schwartz FW. Who is diagnosed as suffering from depression in the German statutory health care system? An analysis of health insurance data. European Journal of Epidemiology. 2007;22:397–403
  7. Burchfiel CM, Curb JD, Rodriguez BL, Abbott RD, Chiu D, Yano K. Glucose intolerance and 22-year stroke incidence: The Honolulu Heart Program. Stroke. 1994;25:951–957
  8. Diabetes Care and Research in Europe . In: The Saint Vincent Declaration. 1989;World Health Organization, ICP/CLR 034
  9. Donnan GA, Fisher M, Macleod M, Davis SM. Stroke. Lancet. 2008;371:1612–1623
  10. Feigin VL, Lawes CMM, Bennett DA, Anderson CS. Stroke epidemiology: A review of population-based studies of incidence, prevalence, and case fatality in the late 20th century. Lancet Neurology. 2003;2:43–53
  11. Goldstein LB, Adams R, Becker K, Furberg CD, Gorelick PB, Hademenos G, et al. Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association. Stroke. 2001;32:280–299
  12. Grysiewicz R, Thomas K, Pandey DK. Epidemiology of ischemic and hemorrhagic stroke: Incidence, prevalence, mortality, and risk factors. Neurologic Clinics. 2008;26:871–895
  13. Hatano S WHO Collaborative Study on the Control of Stroke in the Community. Experience from a multicenter stroke register: A preliminary report. Bull. World Health Organisation. 1976;54:
  14. Hoffmann F, Jung TI, Felsenberg D, Glaeske G. Pattern of intravenous bisphosphonate use in outpatient care in Germany. Pharmacoepidemiology and Drug Safety. 2008;17:896–903
  15. Hu FB, Stampfer MJ, Haffner SM, Solomon CG, Willett WC, Manson JE. Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes. Diabetes Care. 2002;25:1129–1134
  16. Icks A, Dickhaus T, Hörmann A, Heier M, Giani G, Kuch B, et al. Lower incidence of myocardial infarction in non-diabetic subjects and in diabetic women, but not in diabetic men, in the population aged 25 to 74 years. Findings from the MONICA/KORA myocardial infarction registry in Southern Germany, 1985–2006. Diabetologia. 2009;9:1836–1841
  17. Icks A, Haastert B, Trautner C, Giani G, Glaeske G, Hoffmann F. Incidence of lower-limb amputations in the diabetic compared to the non-diabetic population. Findings from nationwide insurance data, Germany, 2005–2007. Experimental and Clinical Endocrinology & Diabetes. 2009;117:500–504
  18. Icks A, Moebus S, Feuersenger A, Haastert B, Jöckel KH, Giani G. Diabetes prevalence and association with social status-widening of a social gradient? German national health surveys 1990–92 and 1998. Diabet Research Clin Practice. 2007;78:293–297
  19. Jeerakathil T, Johnson JA, Simpson SH, Majumdar SR. Short-term risk for stroke is doubled in persons with newly treated type 2 diabetes compared with persons without diabetes: A population-based cohort study. Stroke. 2007;38:1739–1743
  20. Kissela BM, Khoury J, Kleindorfer D, Woo D, Schneider A, Alwell K, et al. Epidemiology of ischemic stroke in patients with diabetes: The Greater Cincinnati/Northern Kentucky Stroke Study. Diabetes Care. 2005;28:355–359
  21. Kolominsky-Rabas PL, Sarti C, Heuschmann PU, Graf C, Siemonsen S, Neundoerfer B, et al. A prospective community-based study of stroke in Germany: The Erlangen Stroke Project (ESPro). Incidence and case fatality at 1, 3 and 12 months. Stroke. 1998;29:2501–2506
  22. Köster I, von Ferber L, Ihle P, Schubert I, Hauner H. The cost burden of diabetes mellitus: The evidence from Germany-the CoDiM Study. Diabetologia. 2006;9:1498–1504
  23. Le W. Biostatistics. Weinheim: Wiley-VCH; 2003;
  24. Meisinger C, Heier M, Doering A, Thorand B, Loewel H. Prevalence of known diabetes and antidiabetic therapy between 1984/1985 and 2000/2001 in Southern Germany. Diabetologia. 2004;27:2985–2987
  25. Mulnier HE, Seaman HE, Raleigh VS, Soedamah-Muthu SS, Colhoun HM, Lawrenson RA, et al. Risk of stroke in people with type 2 diabetes in the UK: A study using the General Practice Research Database. Diabetologia. 2006;49:2859–2865
  26. Myint PK, Sinha S, Luben RN, Bingham SA, Wareham NJ, Khaw KT. Risk factors for first-ever stroke in the EPIC-Norfolk prospective population-based study. European Journal of Cardiovascular Prevention and Rehabilitation. 2008;15:663–669
  27. Ohira T, Shahar E, Chambless LE, Rosamond WD, Mosley TH, Folsom AR. Risk factors for ischemic stroke subtypes: The Atherosclerosis Risk in Communities Study. Stroke. 2006;37:2493–2498
  28. Petty GW, Brown RD, Whisnat JP, Sicks JD, O'Fallon WM, Wiebers DO. Survival and recurrence after first cerebral infarction. A population-based study in Rochester, Minnesota, 1975 through 1989. Neurology. 1998;50:208–216
  29. Rathmann W, Haastert B, Icks A, Löwel H, Meisinger C, Holle R, et al. High prevalence of undiagnosed diabetes mellitus in Southern Germany: Target populations for efficient screening. The KORA survey 2000. Diabetologia. 2003;46:182–189
  30. Rautio A, Eliasson M, Stegmayr B. Favorable trends in the incidence and outcome in stroke in nondiabetic and diabetic subjects: Findings from the Northern Sweden MONICA Stroke Registry in 1985 to 2003. Stroke. 2008;39:3137–3144
  31. Rothman KJ. Modern epidemiology. Boston, MA: Little Brown; 1986;
  32. Schnee M. Socioeconomic structure and morbidity in statutory health insurances. In:  Böcken J,  Braun B,  Amhof R editor. Health monitor (Gesundheitsmonitor). Gütersloh: Bertelsmann; 2008;p. 88–104(in German)
  33. Sudlow CLM, Warlow CP. Comparing stroke incidence worldwide. Stroke. 1996;27:550–558
  34. The European Registers of Stroke (EROS) Investigators . Incidence of stroke in Europe in the beginning of the 21st century. Stroke. 2009;40:1557–1563
  35. von Ferber L, Köster I, Hauner H. Medical costs of diabetic complications total costs and excess costs by age and type of treatment results of the German CoDiM Study. Experimental and Clinical Endocrinology & Diabetes. 2007;115:97–104
  36. Whisnant JP. Modeling of risk factors for ischemic stroke: The Willis lecture. Stroke. 1997;28:1840–1844
  37. Whisnant JP, Brown RD, Petty GW, O'Fallon WM, Sicks JD, Wiebers DO. Comparison of population-based models of risk factors for TIA and ischemic stroke. Neurology. 1999;53:532–536
  38. Zhang Y, Galloway JM, Welty TK, Wiebers DO, Whisnant JP, Devereux RB, et al. Incidence and risk factors for stroke in American Indians: The Strong Heart Study. Circulation. 2008;118:1577–1584

☆ All authors declare that they have no conflict of interest.

PII: S1056-8727(10)00064-4

doi: 10.1016/j.jdiacomp.2010.05.002

Journal of Diabetes and Its Complications
Volume 25, Issue 2 , Pages 90-96 , March 2011

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