Journal of Diabetes and Its Complications
Volume 25, Issue 2 , Pages 83-89 , March 2011

Improvement in bedtime plasma glucose level serves as a predictor of long-term blood glucose control in patients with Type 2 diabetes: a study with monotherapy of 50/50 premixed insulin analogue three times daily injection

  • Masami Tanaka

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Endocrinology, Tenri Hospital, Nara 632-8552, Japan. Tel.: +81 743 63 5611; fax: +81 743 63 1530.
    • ,
  • Hitoshi Ishii

Received 7 April 2009 ,Revised 27 January 2010 ,Accepted 19 May 2010.

References 

  1. Boden G, Chen X, Urbain JL. Evidence for a circadian rhythm of insulin sensitivity in patients with NIDDM caused by cyclic changes in hepatic glucose production. Diabetes. 1996;45:1044–1050
  2. Cavalot F, Petrelli A, Traversa M, Bonomo K, Fiora E, Conti M, et al. Postprandial blood glucose is a stronger predictor of cardiovascular events than fasting blood glucose in Type 2 diabetes mellitus, particularly in women: lessons from the San Luigi Gonzaga Diabetes Study. Journal of Clinical Endocrinology and Metabolism. 2006;91:813–819
  3. Esposito K, Ciotola M, Maiorino MI, Gualdiero R, Schisano B, Ceriello A, et al. Addition of neutral protamine lispro or insulin glargine to oral Type 2 diabetes regimens for patients with suboptimal glycemic control. A randomized trial. Annals of Internal Medicine. 2008;149:531–539
  4. Hanefeld M, Cagatay M, Petrowitsch T, Neuser D, Petzinna D, Rupp M. Acarbose reduces the risk for myocardial infraction in Type 2 diabetic patients: meta-analysis of seven long-term studies. European Heart Journal. 2004;25:10–16
  5. Ishii H, Anderson JH, Yamamura A, Takeuchi M, Ikeda I. Improvement of glycemic control and quality-of-life by insulin lispro therapy: assessing benefits by ITR-QOL questionnaires. Diabetes Research and Clinical Practice. 2008;81:169–178
  6. Ishii H, Furuya M, Iburi T, Yamagami K, Ishibashi E, Tsujii S. Quality of life in insulin-treated patients. Journal of Japan Diabetes Society. 2008;51:601–608(in Japanese)
  7. Kazda C, Hülstrunk H, Helsberg K, Langer F, Forst T, Hanefeld M. Prandial insulin substitution with insulin lispro or insulin lispro mid mixture vs. basal therapy with insulin glargine: a randomized controlled trials in patients with Type 2 diabetes beginning insulin therapy. Journal of Diabetes and its Complications. 2006;20:145–152
  8. Monnier L, Lapinski H, Colette C. Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of Type 2 diabetic patients. Diabetes Care. 2003;26:881–885
  9. Polonsky BD, Given E, Cauter EV. Twenty-four hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. Journal of Clinical Investigation. 1988;81:442–448
  10. Robibins DC, Beisswenger PJ, Ceriello A, Goldberg RB, Moses RG, Pagkalos EM, et al. Mealtime 50/50 basal+prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels on patients with Type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison. Clinical Therapeutics. 2007;29:2349–2364
  11. Rosenstock J, Ahmann AJ, Colon G, Scism-Bacon J, Jiang H, Martin S. Advancing insulin therapy in Type 2 diabetes previously treated with glargine plus oral agents: prandial premixed (insulin lispro protamine suspension/lispro) versus basal/bolus (glargine/lispro) therapy. Diabetes Care. 2008;31:20–25
  12. Rosenstock J, Davies M, Home PD, Larsen J, Koenen C, Schernthaner G. A randomized, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naïve people with Type 2 diabetes. Diabetologia. 2008;51:408–416
  13. Yokoyama H, Tada J, Kamikawa F, Kanno S, Yokota Y, Kuramitsu M. Efficacy of conversion from bedtime NPH insulin to morning insulin glargine in Type 2 diabetic patients on basal-prandial insulin therapy. Diabetes Research and Clinical Practice. 2006;73:35–40

PII: S1056-8727(10)00049-8

doi: 10.1016/j.jdiacomp.2010.05.001

Journal of Diabetes and Its Complications
Volume 25, Issue 2 , Pages 83-89 , March 2011

Article Tools

* Image Usage & Resolution