Journal of Diabetes and Its Complications
Volume 24, Issue 6 , Pages 375-381 , November 2010

Change from oral antidiabetic therapy to insulin and risk of urinary tract infections in Type 2 diabetic patients: a population-based prescription study

  • Anne Katrine Sanden

      Affiliations

    • Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • Department of Clinical Epidemiology, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • Deceased.
    • ,
  • Martin B. Johansen

      Affiliations

    • Department of Clinical Epidemiology, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • ,
  • Lars Pedersen

      Affiliations

    • Department of Clinical Epidemiology, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • ,
  • Hans-Henrik Lervang

      Affiliations

    • Department of Endocrinology, Aalborg Hospital, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • ,
  • Henrik C. Schønheyder

      Affiliations

    • Department of Clinical Microbiology, Aalborg Hospital, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • ,
  • Reimar W. Thomsen

      Affiliations

    • Department of Clinical Epidemiology, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark
    • Corresponding Author InformationCorresponding author. Department of Clinical Epidemiology, Aarhus University Hospital, Forskningens Hus, Sdr. Skovvej 15, DK-9000 Aalborg, Denmark. Tel.: +45 9932 6905; fax: +45 9932 6914.

Received 26 June 2009 ,Revised 19 December 2009 ,Accepted 27 January 2010.

References 

  1. Benfield T, Jensen JS, Nordestgaard BG. Influence of diabetes and hyperglycaemia on infectious disease hospitalisation and outcome. Diabetologia. 2007;50(3):549–554
  2. Boyko EJ, Fihn SD, Scholes D, Abraham L, Monsey B. Risk of urinary tract infection and asymptomatic bacteriuria among diabetic and nondiabetic postmenopausal women. American Journal of Epidemiology. 2005;161(6):557–564
  3. Boyko EJ, Fihn SD, Scholes D, Chen CL, Normand EH, Yarbro P. Diabetes and the risk of acute urinary tract infection among postmenopausal women. Diabetes Care. 2002;25(10):1778–1783
  4. Brix-Christensen V, Andersen SK, Andersen R, Mengel A, Dyhr T, Andersen NT, et al. Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model. Anesthesiology. 2004;100(4):861–870
  5. Brown JS, Vittinghoff E, Kanaya AM, Agarwal SK, Hulley S, Foxman B. Urinary tract infections in postmenopausal women: effect of hormone therapy and risk factors. Obstetetrics and Gynecology. 2001;98(6):1045–1052
  6. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. Journal of Chronic Diseases. 1987;40(5):373–383
  7. Czaja CA, Rutledge BN, Cleary PA, Chan K, Stapleton AE, Stamm WE. Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Urinary tract infections in women with type 1 diabetes mellitus: survey of female participants in the epidemiology of diabetes interventions and complications study cohort. Journal Urology. 2009;181(3):1129–1134
  8. Das UN. Insulin and inflammation: further evidence and discussion. Nutrition. 2002;18(6):526–527
  9. Foxman B, Barlow R, D'Arcy H, Gillespie B, Sobel JD. Urinary tract infection: self-reported incidence and associated costs. Annals of Epidemiology. 2000;10(8):509–515
  10. Frank L. Epidemiology. When an entire country is a cohort. Science. 2000;287(5452):2398–2399
  11. Friis H, Bro F, Eriksen NR, Mabeck CE, Vejlsgaard R. The effect of reimbursement on the use of antibiotics. Scandinavian Journal of Primary Health Care. 1993;11(4):247–251
  12. Geerlings SE, Stolk RP, Camps MJ, Netten PM, Collet TJ, Hoepelman AI. Risk factors for symptomatic urinary tract infection in women with diabetes. Diabetes Care. 2000;23(12):1737–1741
  13. Gradel KO, Dethlefsen C, Ejlertsen T, Schønheyder HC, Nielsen H. Increased prescription rate of antibiotics prior to non-typhoid Salmonella infections: A one-year nested case-control study. Scandinavian Journal of Infectious Diseases. 2008;40(8):635–641
  14. Ingberg C, Palmer M, Schvarcz E, Åman J. Prevalence of urinary tract symptoms in long-standing Type 1 diabetes mellitus. Diabetes & Metabolism. 1998;24:351–354
  15. Jackson SL, Boyko EJ, Scholes D, Abraham L, Gupta K, Fihn SD. Predictors of urinary tract infection after menopause: a prospective study. American Journal of Medicine. 2004;117(12):903–911
  16. Jeppsson JO, Jerntorp P, Sundkvist G, Englund H, Nylund V. Measurement of hemoglobin A1c by a new liquid-chromatographic assay: methodology, clinical utility, and relation to glucose tolerance evaluated. Clinical Chemistry. 1986;32(10):1867–1872
  17. Justesen T, Korsager B, Kolmos HJ, Gerstoft J. Guideline for use of antibiotics. In:  Hansen MS,  Kampmann JP,  Vej-Hansen B editor. 27th ed.. Medicine Register. Vol. 27:Copenhagen: The Danish Medical Association; 2004;p. 866–868(in Danish)
  18. Peleg AY, Weerarathna T, McCarthy JS, Davis TM. Common infections in diabetes: pathogenesis, management and relationship to glycaemic control. Diabetes/Metabolism Research and Reviews. 2007;23(1):3–13
  19. Rassias AJ, Marrin CA, Arruda J, Whalen PK, Beach M, Yeager MP. Insulin infusion improves neutrophil function in diabetic cardiac surgery patients. Anesthesia and Analgesia. 1999;88(5):1011–1016
  20. Ribera MC, Pascual R, Orozco D, Perez BC, Pedrera V, Gil V. Incidence and risk factors associated with urinary tract infection in diabetic patients with and without asymptomatic bacteriuria. European Journal of Clinical Microbiology & Infectious Diseases. 2006;25(6):389–393
  21. Schonheyder HC, Thrane N, Sorensen HT. Repeat antibiotic prescriptions following treatment with sulfonamide or pivmecillinam. A survey of prescriptions among women aged 15-50 years in the county of Nordjylland. Ugeskrift for Laeger. 2001;164(1):43–46
  22. Shah BR, Hux JE. Quantifying the risk of infectious diseases for people with diabetes. Diabetes Care. 2003;26(2):510–513
  23. Thomsen RW, Hundborg HH, Lervang HH, Johnsen SP, Schonheyder HC, Sorensen HT. Diabetes mellitus as a risk and prognostic factor for community-acquired bacteremia due to enterobacteria: a 10-year, population-based study among adults. Clinical Infectious Diseases. 2005;40(4):628–631
  24. UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352(9131):837–853
  25. Vinther PM, Christensen S, Thomsen RW. Sygehuskontakter og lægemiddelforbrug for udvalgte kroniske sygdomme i Region Nordjylland [report in Danish]. Aarhus, Denmark: Aarhus University Hospital, Department of Clinical Epidemiology; 2007;Available from: http://kea.au.dk/files/36.pdf(accessed 24 June 2009)

☆ This study was supported by grants from the Afdelingen for Universitetshospitalsanliggender, Aalborg Hospital, Aarhus University Hospital; Forskningsinitiativet, Aarhus University; and Klinisk epidemiologisk forskningsfond, Aarhus University.

☆☆ Preliminary results in abstract form were presented at the 18th European Congress of Clinical Microbiology and Infectious Diseases, Barcelona, Spain 19-22 April 2008, abstract P1623.

PII: S1056-8727(10)00003-6

doi: 10.1016/j.jdiacomp.2010.01.002

Journal of Diabetes and Its Complications
Volume 24, Issue 6 , Pages 375-381 , November 2010

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