Journal of Diabetes and Its Complications
Volume 24, Issue 4 , Pages 265-269 , July 2010

Mortality after major amputation in diabetic patients with critical limb ischemia who did and did not undergo previous peripheral revascularization: Data of a cohort study of 564 consecutive diabetic patients

  • Ezio Faglia

      Affiliations

    • Diabetology Center-Diabetic Foot Center, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • ,
  • Giacomo Clerici

      Affiliations

    • Diabetology Center-Diabetic Foot Center, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • Corresponding Author InformationCorresponding author. Diabetology Center-Diabetic Foot Center, IRCCS MultiMedica, Via Milanese 300, 20099 Sesto San Giovanni (Milan), Italy. Tel.: +39 02 24209466; fax: +39 02 24209085.
    web address
    • ,
  • Maurizio Caminiti

      Affiliations

    • Diabetology Center-Diabetic Foot Center, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • ,
  • Vincenzo Curci

      Affiliations

    • Diabetology Center-Diabetic Foot Center, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • ,
  • Jacques Clerissi

      Affiliations

    • Interventional Radiology Unit, IRCCS Multimedica Sesto San Giovanni (Milano), Italy
    • ,
  • Sergio Losa

      Affiliations

    • Vascular Surgery Unit, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • ,
  • Andrea Casini

      Affiliations

    • Vascular Surgery Unit, IRCCS Multimedica, Sesto San Giovanni (Milano), Italy
    • ,
  • Alberto Morabito

      Affiliations

    • Medical Statistics Unit, University of Milan, Italy

Received 3 October 2007 ,Revised 21 January 2009 ,Accepted 11 February 2009.

References 

  1. Aulivola B, Hile CN, Hamdan AD, Sheahan MG, Veraldi JR, Skillman JJ, et al. Major lower extremity amputation: outcome of a modern series. Archives of Surgery. 2004;139:395–399
  2. Faglia E, Clerici G, Clerissi J, Gabrielli L, Losa S, Mantero M, et al. Early and five-year amputation and survival rate of diabetic patients with critical limb ischemia: data of a cohort study of 564 patients. European Journal of Vascular and Endovascular Surgery. 2006;32:484–490
  3. Faglia E, Clerici G, Clerissi J, Mantero M, Caminiti M, Quarantiello A, et al. When is a technically successful peripheral angioplasty effective to prevent the above-the-ankle amputation in diabetic patients with critical limb ischemia?. Diabetic Medicine. 2007;accepted 2 February 2007
  4. Garbalosa JC, Cavanagh PR, Wu G, Ulbrecht JS, Becker MB, Alexander IJ, et al. Foot function in diabetic patients after partial amputation. Foot and Ankle International. 1996;17:43–48
  5. Kulkarni J, Pande S, Morris J. Survival rates in dysvascular lower limb amputees. International Journal of Surgery. 2006;4:217–221
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  8. Moulik PK, Mtonga R, Gill GV. Amputation and mortality in new-onset diabetic foot ulcers stratified by etiology. Diabetes Care. 2003;26:491–494
  9. Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FGR on behalf of the TASC II Working Group. Inter-society consensus for the management of peripheral arterial disease (TASC II). European Journal of Vascular and Endovascular Surgery. 2007;33(Suppl):S73–S108
  10. Nowygrod R, Egorova N, Greco G, Anderson P, Gelijns A, Moskowitz A, et al. Trends, complications, and mortality in peripheral vascular surgery. Journal of Vascular Surgery. 2006;43:205–216
  11. Ploeg AJ, Lardenoye JW, Vrancken Peeters MP, Breslau PJ. Contemporary series of morbidity and mortality after lower limb amputation. European Journal of Vascular and Endovascular Surgery. 2005;29:633–637
  12. Pounds LL, Montes-Walters M, Mayhall CG, Falk PS, Sanderson E, Hunter GC, et al. A changing pattern of infection after major vascular reconstructions. Vascular and Endovascular Surgery. 2005;39:511–517
  13. Reyzelman AM, Hadi S, Amstrong DG. Limb salvage with Chopart's amputation and tendon balancing. Journal of American Podiatry Association. 1999;9:100–103
  14. Ryer EJ, Trocciola SM, DeRubertis B, Lam R, Hynecek RL, Karwowski J, et al. Analysis of outcomes following failed endovascular treatment of chronic limb ischemia. Annals of Vascular Surgery. 2006;20:440–446
  15. Subramaniam B, Pomposelli F, Talmor D, Park KW. Perioperative and long-term morbidity and mortality after above-knee and below-knee amputations in diabetics and nondiabetics. Anesthesia Analgesia. 2005;100:1241–1247
  16. Taylor SM, Kalbaugh CA, Blackhurst DW, Kellicut DC, Langan EM, Youkey A. Comparison of percutaneous transluminal angioplasty versus amputation for critical limb ischemia in patients unsuitable for open surgery. Journal of Vascular Surgery. 2007;45:304–310
  17. Tentolouris N, Al-Sabbagh S, Walker MG, Boulton AJ, Jude EB. Mortality in diabetic and nondiabetic patients after amputations performed from 1990 to 1995: a 5-year follow-up study. Diabetes Care. 2004;27:1598–1604
  18. TransAtlantic Inter-Society Consensus (TASC) . Management of peripheral arterial disease (PAD). European Journal of Vascular and Endovascular Surgery. 2000;19(Suppl A):208–290
  19. Van Damme H. Crural or pedal artery revascularization for limb salvage: is it justified?. Acta Chirurgica Belgica. 2004;104:148–157

PII: S1056-8727(09)00027-0

doi: 10.1016/j.jdiacomp.2009.02.004

Journal of Diabetes and Its Complications
Volume 24, Issue 4 , Pages 265-269 , July 2010

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