Journal of Diabetes and Its Complications
Volume 23, Issue 2 , Pages 130-136 , March 2009

Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin-induced Type 1 diabetes

  • Mohamed A. Haidara

      Affiliations

    • Physiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • ,
  • Dimitri P. Mikhailidis

      Affiliations

    • Department of Clinical Biochemistry (Vascular Prevention Clinic), Royal Free Hospital, Royal Free, London, UK
    • University College Medical School (University of London), London, UK
  • ,
  • Moshira A. Rateb

      Affiliations

    • Physiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
    • Corresponding Author InformationCorresponding author. Physiology Department, Faculty of Medicine, Kasr El Aini Hospital, Manial El Roda, Cairo University, Cairo, Egypt. Tel.: (202) 2516 5916; Mobile: +20 10 6224104; fax: (202) 2516 5916.
  • ,
  • Zeinab A. Ahmed

      Affiliations

    • Physiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • ,
  • Hanaa Z. Yassin

      Affiliations

    • Physiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • ,
  • Ibrahim M. Ibrahim

      Affiliations

    • Physiology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
  • ,
  • Laila A. Rashed

      Affiliations

    • Biochemistry Department, Faculty of Medicine, Cairo University, Cairo, Egypt

Received 2 May 2007 ,Revised 9 February 2008 ,Accepted 28 February 2008.

References 

  1. Angula J, Cuevas P, Fernandez A, Gabancho S, Allona A, Martin- Morales A, et al. Activation and potentiation of the NO/cGMP pathway by NG- hydroxyl-l-arginine in rabbit corpus cavernosum under normoxic and hypoxic condition and aging. Br J Pharmacol. 2003;138:63–70
  2. Athyros VG, Elisaf M, Papageorgiou AA, Symeonidis AN, Pehlivanidis AN, Bouloukos VI, et al. Effect of statins versus untreated dyslipidemia on serum uric acid levels in patients with coronary heart disease: A subgroup analysis of the GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) study. American Journal of Kidney Diseases. 2004;43(4):589–599
  3. Athyros VG, Mikhailidis DP, Papageorgiou AA, Symeonidis AN, Pehlivanidis AN, Bouloukos VI, et al. The effect of statins versus untreated dyslipidaemia on renal function in patients with coronary heart disease. A subgroup analysis of the Greek atorvastatin and coronary heart disease evaluation (GREACE) study. Journal of Clinical Pathology. 2004;57(7):728–734
  4. Athyros VG, Mikhailidis DP, Liberopoulos EN, Kakafika AI, Karagiannis A, Papageorgiou AA, et al. Effect of statin treatment on renal function and serum uric acid levels and their relation to vascular events in patients with coronary heart disease and metabolic syndrome: A subgroup analysis of the GREek Atorvastatin and Coronary heart disease Evaluation (GREACE) Study. Nephrology, Dialysis, Transplantation. 2007;22(1):118–127
  5. Bretaudiere JP, Thieu-Phung H, Baily H. Direct enzymatic determination of urea in the plasma and urine with a centrifugal analyzer. Clinical Chemistry. 1976;22:1614–1617
  6. Caramori ML, Kim Y, Huang C, Fish AJ, Rich SS, Miller ME, et al. Cellular basis of diabetic nephropathy: 1. Study design and renal structural-functional relationships in patients with long-standing type 1 diabetes. Diabetes. 2002;51:506–513
  7. Cardillo C, Nambi SS, Kilcoyne CM. Insulin stimulates both endothelium and nitric oxide activity in the human forearm. Circulation. 1999;100:820–825
  8. Collins R, Armitage J, Parish S, Sleigh P, Peto R Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: A randomised placebo-controlled trial. Lancet. 2003;361:2005–2016
  9. Devaraj S, Jialal I. The effect of a-tocopherol supplementation on monocyte function. The Journal of Clinical Investigation. 1996;98:756–763
  10. The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The New England Journal of Medicine. 1993;329:977–986
  11. Draper HH, Hadley M. Assessment of malondialdehyde method. Enzymology. 1991;186:421–443
  12. Esqueda DME, Hernández VA, Morales MF. Comparative analysis of the renoprotective effects of pentoxifylline and vitamin E on streptozotocin-induced diabetes mellitus. Renal Failure. 2005;27(1):115–122
  13. Flohe R, Kelly F. The European perspective of Vit. E. The American Journal of Clinical Nutrition. 2002;76:703–716
  14. Gisinger C, Jeremy J, Speiser P, Mikhailidis D, Dandona P, Schernthaner G. Effect of vitamin E supplementation on platelet thromboxane A2 production in type I diabetic patients. Double-blind crossover trial. Diabetes. 1988;37:1260–1264
  15. Ha H, Kim KH. Pathogenesis of diabetic nephropathy: The role of oxidative stress and protein kinase C. Diabetes Research and Clinical Practice. 1999;45:147–151
  16. Haidara M, Desoky A, Khlousy H, Sebaee H. The mechanisms underlying the development of hypertension in STZ induced diabetic rats. Progress in Medical Research. 2004;2:1–18
  17. Haidara M, Khloussy H, Ammar H, Aal Kassem LA. Impact of alpha-tocopherol and vitamin C on endothelial markers in rats with streptozotocin-induced diabetes. Medical Science Monitor. 2004;10(2):BR41–BR46
  18. Haidara M, Yassin H, Rateb M, Ammar H, Zorkani M. Role of oxidative stress in development of cardiovascular complications in diabetes mellitus. Current Vascular Pharmacology. 2006;4:215–227
  19. Horton JW, White DJ, Maass DL, Hybki DP, Haudek S, Giroir B. Antioxidant vitamin therapy alters burn trauma mediated cardiac NF-kB activation and cardiomyocyte cytokine secretion. Trauma. 2001;50:397–406
  20. Hsu C, Bates D, Kuperman G, Curhan G. Diabetes, hemoglobin A (1c) cholesterol and the risk of moderate chronic renal insufficiency in an ambulatory population. American Journal of Kidney Diseases. 2001;36:272–281
  21. Ishii H, Jirousek MR, Koya D, Takagi C, Xia P, Clermont A, et al. Amelioration of vascular dysfunction in diabetic rats by an oral protein kinase beta inhibitor. Science. 1996;272:728–731
  22. Ishii N, Patel KP, Lane PH, Taylor T, Bian K, Murad F, et al. Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus. Journal of the American Society of Nephrology. 2001;12:1630–1639
  23. Iwashina M, Shichiri M, Marumo F, Hirata Y. Transfection of inducible nitric oxide synthase gene causes apoptosis in vascular smooth muscle cells. Circulation. 1998;98:1212–1218
  24. Kessler P, Bauersachs J, Busse R, Schini-Kerth VB. Inhibition of inducible nitric oxide synthase restores endothelium-dependent relaxations in pro-inflammatory mediator-induced blood vessels. Arteriosclerosis, Thrombosis, and Vascular Biology. 1997;17:1746–1755
  25. Knoll K, Pietrusz J, Liang M. Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. Physiological Genomics. 2005;21:222–229
  26. Koya D, Lee I, Ishii H, Kanoh H, King G. Prevention of glomerular dysfunction in diabetic rats by treatment with d-a-tocopherol. Journal of the American Society for Nephrology. 1997;8:426–435
  27. Koya D, Hayashi K, Kitada M, Kashiwagi A, Kikkawa R, Haneda M. Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. American Society of Nephrology. 2003;14:S250–S253
  28. Lee HB, Yu MR, Yang Y, Jiang Z, Ha H. Reactive oxygen species-regulated signalling pathways in diabetic nephropathy. Journal of the American Society for Nephrology. 2003;14:S241–S245
  29. Marletta MA. Nitric oxide: biosynthesis and biological significance. Trends in Pharmacological Sciences. 1989;158:348–352
  30. Mauer M, Fioretto P, Woredekal Y, Friedman EA. Diabetic nephropathy. In:  Schrier RW editors. Diseases of the kidney. (7th ed.). Philadelphia: Lippincott Williams & Wilkins; 2001;
  31. Mauer M, Drummond K. The International Diabetic Nephropathy Study Group: The early natural history of nephropathy in type 1 diabetes: 1. Study design and baseline characteristics of the study participants. Diabetes. 2002;51:1572–1579
  32. Michel T, Feron O. Nitric oxide synthases: Which, where, how, and why?. The Journal of Clinical Investigation. 1997;100:2146–2152
  33. Moncada S, Higgs EA. The l-arginine-nitric oxide pathway. The New England Journal of Medicine. 1993;329:2002–2012
  34. Mustata G, Rosca M, Biemel K, Reihl O, Smith M, Viswanathan A, et al. Paradoxical effects of green tea (Camellia sinensis) and antioxidant vitamins in diabetic rats improved retinopathy and renal mitochondrial defects but deterioration of collagen matrix glycoxidation and cross-linking. Diabetes. 2005;54:517–526
  35. Nathan C. Inducible nitric oxide synthase: what difference does it make?. The Journal of Clinical Investigation. 1997;100:2417–2423
  36. Noh H, Ha H, Yu MR, Kang SW, Choi KH, Han DS, et al. High glucose increases inducible NO production in cultured rat mesangial cells. Possible role in fibronectin production. Nephron. 2002;90:78–85
  37. Pagalia DE, Valentine WN. Studies on quantitative and qualitative characterization of erythrocyte GPx. The Journal of Laboratory and Clinical Medicine. 1967;70:158
  38. Powell L, Warpeha K, Xu W, Walker B, Trimble E. High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells. Journal of Molecular Endocrinology. 2004;33:797–803
  39. Ritz E, Keller C, Bergis K, Strojek K. Pathogenesis and course of renal disease in IDDM/NIDDM: differences and similarities. American Journal of Hypertension. 1997;10:202S–207S
  40. Sen CK, Packer LT. Homeostasis and supplements in physical exercise. The American Journal of Clinical Nutrition. 2000;72:653–695
  41. Shimabukuro M, Ohneda M, Lee Y, Unger R. Role of nitric oxide in obesity-induced b cell disease. The Journal of Clinical Investigation. 1997;100:290–295
  42. Sun L, Halaihel N, Zhang W, Rogers T, Levi M. Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. The Journal of Biological Chemistry. 2002;277:18919–18927
  43. Tietz NW. In: Fundamentals of clinical chemistry. 3rd edition. W.B. Saunder Company; 1987;p. 68
  44. Trinder P. Enzymatic determination of blood glucose. Annals of Clinical Biochemistry. 1969;6:24–26
  45. United States Renal Data System (USRDS). 2000 Annual data report. Bethesda, MD: National Institutes of Health; 2000;
  46. Wheatcrot SB, Kearney MT, Shah AM, Grieve DJ, Williams IL, Miell JP, et al. Endothelial function and blood pressure homeostasis in mice over expressing IGF binding protein-1. Diabetes. 2003;52:2075–2082
  47. Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. The Journal of Biological Chemistry. 1998;273:25804–25808
  48. Xu R, Morales JA, Muniyappa R, Skafar DF, Ram JL, Sowers JR. IL-1-induced nitric oxide production in rat aortic endothelial cells: Inhibition by estradiol in normal and high glucose cultures. Life Sciences. 1999;64:2451–2462
  49. Yechoor VK, Patti ME, Saccone R, Kahn CR. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 2002;99:10587–10592

PII: S1056-8727(08)00034-2

doi: 10.1016/j.jdiacomp.2008.02.011

Journal of Diabetes and Its Complications
Volume 23, Issue 2 , Pages 130-136 , March 2009