Journal of Diabetes and Its Complications
Volume 23, Issue 2 , Pages 89-94 , March 2009

The relationship between glycemic control and platelet activity in type 2 diabetes mellitus

  • Refik Demirtunc

      Affiliations

    • Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
  • ,
  • Dursun Duman

      Affiliations

    • Department of Cardiology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +90 216 4491151.
  • ,
  • Melih Basar

      Affiliations

    • Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
  • ,
  • Mustafa Bilgi

      Affiliations

    • Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
  • ,
  • Mehmet Teomete

      Affiliations

    • Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
  • ,
  • Tayfun Garip

      Affiliations

    • Department of Internal Medicine, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey

Received 24 May 2007 ,Revised 7 January 2008 ,Accepted 18 January 2008.

References 

  1. Alessandrini P, Me Rae J, Feman S, Fitzgerald GA. Thromboxane biosynthesis and platelet function in type I diabetes mellitus. New England Journal of Medicine. 1988;319:208–212
  2. Arauz-Pacheco C, Parrott MA, Raskin P. The treatment of hypertension in adult patients with diabetes. (Technical Review) Diabetes Care. 2002;25:134–147
  3. Aydınlı S, Saydam G, Şahin F, Tüzün M, Büyükkeçeci F. The relationship between mean platelet volume, in-vitro platelet function tests and microvascular complications in type 2 diabetes mellitus. Turk Hematoloji Onkoloji Dergisi. 2004;14:193–199
  4. Bancroft AJ, Abel EW, Mclaren M, Belch JJF. Mean platelet volume is a useful parameter: A reproducible routine method using a modified Coulter thrombocytometer. Platelets. 2000;11:379–387
  5. Bath PM, Butterworth RJ. Platelet size: Measurement, physiology and vascular disease. Blood Coagulation & Fibrinolysis. 1996;7:157–161
  6. Bath PMW, Missouris CG, Buckenham T, MacGregor GA. Increased platelet volume and platelet mass in patients with atherosclerotic renal artery stenosis. Clinical Science. 1994;87:253–257
  7. Bick RL. Platelet function defects: A clinical review. Seminars in Thrombosis and Hemostasis. 1992;18:167–181
  8. Ceyhan T, Beyan C, Baser I, Kaptan K, Gungor S, Ifran A. The effect of pre-eclampsia on complete blood count, platelet count and mean platelet volume. Annals of Hematology. 2006;85:320–322
  9. Cox D. Methods for monitoring platelet function. American Heart Journal. 1998;135:160–169
  10. Demirtunc R, Duman D, Basar M. Effects of doxazosin and amlodipine on mean platelet volume and serum serotonin level in patients with metabolic syndrome: A randomised, controlled study. Clinical Drug Investigation. 2007;27:435–441
  11. Early Treatment Diabetic Retinopathy Research Group. Grading diabetic retinopathy from steroscopic color fundus photographs: An extension of the modified Airlie House classification: ETDRS report number 10. Ophthalmology. 1991;18:786–806
  12. Hekimsoy Z, Payzin B, Ornek T, Kandogan G. Mean platelet volume in type 2 diabetic patients. Journal of Diabetes and its Complications. 2004, May–June;18(3):173–176
  13. Hendra TJ, Oswald GA, Yudkin JS. Increased mean platelet volume after acute myocardial infarction relates to diabetes and to cardiac failure. Diabetes research and Clinical Practice. 1988;5(1):63–69
  14. Huczek Z, Kochman J, Filipiak KJ, et al. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. Journal of the American College of Cardiology. 2005, July;46:284–290
  15. Jagroop IA, Mikhailidis DP. Doxazosin, an alpha1-adrenoceptor antagonist, inhibits serotonin-induced shape change in human platelets. Journal of Human Hypertension. 2001;15:203–207
  16. O'Malley T, Langhome P, Elton RA, Stewart C. Platelet size in stroke patients. Stroke. 1995;26:995–999
  17. Papanas N, Symeonidis G, Maltezos E, et al. Mean platelet volume in patients with type 2 diabetes mellitus. Platelets. 2004;15:475–478
  18. Perkins BA, Olaleye D, Zinman B, Bril V. Simple screening tests for peripheral neuropathy in the diabetes clinic. Diabetes Care. 2001;24:250–256
  19. Sharpe PC, Trinick T. Mean platelet volume in diabetes mellitus. Quarterly Journal of Medicine. 1993, November;86(11):739–742
  20. Stettler C, Allemann S, Juni P, Cull CA, Holman RR, Egger M, et al. Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: Meta-analysis of randomized trials. American Heart Journal. 2006;152:27–38
  21. Symth DW, Martin JF, Michalis L, et al. Influence of platelet size before coronary angioplasty on subsequent restenosis. European Journal of Clinical Investigation. 1993;23:361–367
  22. Thompson CB, Jakubowski JA. Platelet size as a determinant of platelet function. Journal of Laboratory and Clinical Medicine. 1983;101/2:205–213
  23. Tschope D, Langer E, Schauseil S, Rosen P, Kaufmann L, Gries FA. Increased platelet volume—Sign of impaired thrombopoiesis in diabetes mellitus. Klinische Wochenschrift. 1989;15(7):253–259
  24. Tsiara S, Elisaf M, Jagroop IA, Mikhailidis DP. Platelets as predictors of vascular risk: Is there a practical index of platelet activity?. Clinical and Applied Thrombosis/Hemostasis. 2003;9:177–190
  25. Van der Loo B, Martin JF. A role for changes in platelet production in the cause of acute coronary syndromes. Arteriosclerosis, Thrombosis, and Vascular Biology. 1999;19:672–679
  26. Vicari AM, Macagni A. Primary platelet activation in recent-onset type 1 diabetes mellitus. Scandinavian Journal of Clinical and Laboratory Investigation. 1990;50:429–432
  27. Vinik AI, Erbas T, Park TS, Nolan R, Pittenger GL. Platelet dysfunction in type 2 diabetes. Diabetes Care. 2001;24:1476–1485
  28. Winocour P. Platelets, vascular disease, and diabetes mellitus. Canadian Journal of Physiology and Pharmacology. 1994;72:295–303
  29. Yang A, Pizzulli L, Luderitz B. Mean platelet volume as marker of restenosis after percutaneous transluminal coronary angioplasty in patients with stable and unstable angina pectoris. Thrombosis Research. 2006;117:371–377

PII: S1056-8727(08)00010-X

doi: 10.1016/j.jdiacomp.2008.01.006

Journal of Diabetes and Its Complications
Volume 23, Issue 2 , Pages 89-94 , March 2009