Journal of Diabetes and Its Complications
Volume 21, Issue 3 , Pages 149-157, May 2007

Obesity impairs vascular relaxation in human subjects: hyperglycemia exaggerates adrenergic vasoconstriction:☆

Arterial dysfunction in obesity and diabetes

  • William I. Sivitz

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, IA 52242, USA
    • University of Iowa General Clinical Research Center, Iowa City, IA, USA
    • Corresponding Author InformationCorresponding author. Division of Endocrinology, Department of Internal Medicine, University of Iowa Health Care, 200 Hawkins Drive, Iowa City, IA 52242, USA. Tel.: +1 319 353 7710; fax: +1 319 353 7850.
    • ,
  • Sheila M. Wayson

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, IA 52242, USA
    • University of Iowa General Clinical Research Center, Iowa City, IA, USA
    • ,
  • Margaret L. Bayless

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, IA 52242, USA
    • University of Iowa General Clinical Research Center, Iowa City, IA, USA
    • ,
  • Christine A. Sinkey

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, IA 52242, USA
    • University of Iowa General Clinical Research Center, Iowa City, IA, USA
    • ,
  • William G. Haynes

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Iowa City Veterans Affairs Medical Center and the University of Iowa, Iowa City, IA 52242, USA
    • University of Iowa General Clinical Research Center, Iowa City, IA, USA

Received 7 October 2005; received in revised form 7 December 2005; accepted 29 December 2005.

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☆ Supported by the Department of Veterans Affairs Office of Research and Development, the Juvenile Diabetes Foundation International, grant DK25295 from the NIH, and by grant M01-RR00059, National Center for Research Resources, General Clinical Research Centers Program, NIH.

PII: S1056-8727(06)00004-3

doi:10.1016/j.jdiacomp.2005.12.003

Journal of Diabetes and Its Complications
Volume 21, Issue 3 , Pages 149-157, May 2007

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