Journal of Diabetes and Its Complications
Volume 20, Issue 4 , Pages 216-223 , July 2006

Exercise training can modify the natural history of diabetic peripheral neuropathy

  • Stefano Balducci

      Affiliations

    • Health Care Team, Metabolic Fitness Association, Monterotondo, Rome, Italy
    • Department of Clinical Sciences, Endocrinology, University of Rome, La Sapienza, Rome, Italy
    • ,
  • Gianluca Iacobellis

      Affiliations

    • Department of Clinical Sciences, Endocrinology, University of Rome, La Sapienza, Rome, Italy
    • Center for Human Nutrition, The University of Texas Southwestern Medical Center at Dallas, TX 75390-9052, USA
    • Corresponding Author InformationCorresponding author. Fax: +1 214 648 7150
    • ,
  • Leoluca Parisi

      Affiliations

    • Department of Clinical Neurology, La Sapienza University, Rome, Italy
    • ,
  • Nicolina Di Biase

      Affiliations

    • Health Care Team, Metabolic Fitness Association, Monterotondo, Rome, Italy
    • St. Pietro Hospital, FBF, Rome, Italy
    • ,
  • Eugenio Calandriello

      Affiliations

    • Health Care Team, Metabolic Fitness Association, Monterotondo, Rome, Italy
    • Department of Clinical Neurology, La Sapienza University, Rome, Italy
    • ,
  • Frida Leonetti

      Affiliations

    • Department of Clinical Sciences, Endocrinology, University of Rome, La Sapienza, Rome, Italy
    • ,
  • Francesco Fallucca

      Affiliations

    • Department of Clinical Sciences, La Sapienza University II Faculty (St. Andrea Hospital), Rome, Italy

Received 26 August 2004 ,Revised 25 February 2005 ,Accepted 5 July 2005.

  • Image Result

    Change in NCV (ΔNCV) from baseline to the end of the study; ⁎⁎P<.001.

    Change in NCV (ΔNCV) from baseline to the end of the study; ⁎⁎P<.001.

  • Image Result

    Percentage of patients developing (A) motor neuropathy, (B) sensory neuropathy, and (C) VPT ≥25 V during 4 years of follow-up in the (– –) control and (—) exercise group.

    Percentage of patients developing (A) motor neuropathy, (B) sensory neuropathy, and (C) VPT ≥25 V during 4 years of follow-up in the (– –) control and (—) exercise group.

  • Image Result

    Malleulus and Hallux VPT at baseline and after 4 years on the control and exercise groups; *P<.05.

    Malleulus and Hallux VPT at baseline and after 4 years on the control and exercise groups; *P<.05.

PII: S1056-8727(05)00090-5

doi: 10.1016/j.jdiacomp.2005.07.005

Journal of Diabetes and Its Complications
Volume 20, Issue 4 , Pages 216-223 , July 2006

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