Journal of Diabetes and Its Complications
Volume 18, Issue 6 , Pages 336-342 , November 2004

Erythrocytic sorbitol contents in diabetic patients correlate with blood aldose reductase protein contents and plasma glucose levels, and are normalized by the potent aldose reductase inhibitor fidarestat (SNK-860)

  • Tomoichiro Asano

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +81-3-3815-5411 x33133; fax: +81-3-5803-1874
    • Department of Physiological Chemistry and Metabolism, The University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan
    • ,
  • Yasushi Saito

      Affiliations

    • Second Department of Internal Medicine, Chiba University School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-0856, Japan
    • ,
  • Masanobu Kawakami

      Affiliations

    • Department of General Medicine, Omiya Medical Center, Jichi Medical School, 1-847 Amanuma, Omiya-ku, Saitama 330-8503, Japan
    • ,
  • Nobuhiro Yamada

      Affiliations

    • Institute of Clinical Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki 305-8576, Japan
    • ,
  • Hisakuni Sekino

      Affiliations

    • Sekino Clinical Pharmacology Clinic, 28-3, Ikebukuro 3 chome, Toshima-ku, Tokyo 171-0014, Japan
    • ,
  • Setsuo Hasegawa

      Affiliations

    • Sekino Clinical Pharmacology Clinic, 28-3, Ikebukuro 3 chome, Toshima-ku, Tokyo 171-0014, Japan
    • ,
  • Fidarestat Clinical Pharmacology Study Group

Received 5 May 2003 ,Revised 17 March 2004 ,Accepted 6 April 2004.

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PII: S1056-8727(04)00037-6

doi: 10.1016/j.diacomp.2004.04.003

Journal of Diabetes and Its Complications
Volume 18, Issue 6 , Pages 336-342 , November 2004

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