Journal of Diabetes and Its Complications
Volume 18, Issue 6 , Pages 322-327 , November 2004

Association between hematological parameters and metabolic syndrome components in a Chinese population

  • Ya-Yu Wang

      Affiliations

    • Department of Family Medicine, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, No. 160, Section 3, Chung-Gang Road, Taichung 407, Taiwan, ROC
    • ,
  • Shih-Yi Lin

      Affiliations

    • Department of Medicine, Division of Endocrinology and Metabolism, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, Taiwan, ROC
    • ,
  • Pi-Haw Liu

      Affiliations

    • Department of Family Medicine, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, No. 160, Section 3, Chung-Gang Road, Taichung 407, Taiwan, ROC
    • ,
  • Bruno M.H. Cheung

      Affiliations

    • Department of Family Medicine, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, No. 160, Section 3, Chung-Gang Road, Taichung 407, Taiwan, ROC
    • ,
  • Wen-An Lai

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +886-4-23592535x3801; fax: +886-4-24617638
    • Department of Family Medicine, Taichung Veterans General Hospital, National Yang-Ming University School of Medicine, No. 160, Section 3, Chung-Gang Road, Taichung 407, Taiwan, ROC

Received 13 June 2003 ,Revised 12 January 2004 ,Accepted 16 January 2004.

References 

  1. Aoki I, Taniyama M, Toyoma K, Homori M, Ishikawa K. Stimulatory effects of human insulin on erythroid progenitors (CFU-E and BFU-E) in human CD34 separated bone marrow cells and the relationship between insulin and erythropoietin. Stem Cells. 1994;12:329–338
  2. Athens JW. Granulocytes–neutrophils. In:  Lee CR editors. Wintrotrobe's clinical hematology. 9th ed.. Philadelphia: Lea and Ferbinger; 1993;p. 247–248
  3. Barbieri M, Ragno E, Benvenuti E, Zito GA, Corsi A, Ferrucci L, et al. New aspects of insulin resistance syndrome: impact on haematological parameters. Diabetologia. 2001;44:1232–1237
  4. Berg LN, Bonaa KH, Nordoy A. Serum ferritin and cardiovascular risk factors in healthy women. Atheriosclerosis and Thrombosis. 1994;14:857–861
  5. Bersch N, Groopman JE, Golde DW. Natural and synthetic insulin stimulates the growth of human erythroid progenitors in vitro. Journal of Clinical Endocrinology and Metabolism. 1982;55:1209–1211
  6. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults . Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection. Evaluation and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2496
  7. Facchini F, Hollenbeck CB, Chen YN, Chen YDI, Reaven GM. Demonstration of a relationship between white blood cell count, insulin resistance, and several risk factors of coronary heart disease in women. Journal of Internal Medicine. 1992;232:267–272
  8. Fernandez-Real JM, Penarroja G, Castro A, Garcia-Bragado F, Hernandez-Aguado I, Ricart W. Blood letting in high-ferritin type 2 diabetes: effect on insulin sensitivity and β-cell function. Diabetes. 2002;51:1000–1004
  9. Fernandez-Real JM, Ricart W. Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness. Diabetologia. 1999;42:1367–1374
  10. Fernandez-Real JM, Vayreda M, Richart C, Gutierrez C, Broch M, Vendrell J, et al. Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women. Journal of Clinical Endocrinology and Metabolism. 2001;86:1154–1159
  11. Friedman GD, Teskawa I, Grimm RH, Manolio T, Shannon SG, Sidney S. The leukocyte count: correlates and relationship to coronary risks factors: the CARDIA study. International Journal of Epidemiology. 1990;19:889–893
  12. Friedman M, St George S, Byers SO. Excretion of catecholamines, 17-ketosteroids, 17-hydroxycoids and 5-hydroxyindole in men exhibiting a particular behavior pattern (A) associated with high incidence of clinical coronary artery disease. Journal of Clinical Investigation. 1960;39:758–764
  13. Grundy SM. Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. American Journal of Cardiology. 1999;83:25F–29F
  14. Haffner SM, Valdez RA, Hazuda HP, Mitchell BD, Morales PA, Stern MP. Prospective analysis of the insulin resistance syndrome (syndrome X). Diabetes. 1992;41:715–722
  15. Hansen LK, Grimm RH, Neaton JD. The relationship of white blood cell count to the other cardiovascular risk factors. International Journal of Epidemiology. 1990;19:881–888
  16. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science. 1993;259:87–91
  17. Howell RW. Smoking habits and laboratory tests. Lancet. 1970;2:152
  18. Jeppesen JL, Maheux P, Facchini FS. White blood cell count and insulin resistance in healthy nonsmoking men. American Heart Journal. 1994;127:459–461
  19. Juhan-Vague I, Thomson SG, Jespersen J. Involvement of the hemostatic system in the insulin resistance syndrome. A study of 1500 patients with angina pectoris. Arteriolosclerosis and Thrombosis. 1993;13:1865–1873
  20. Kanazawa M, Yoshiike N, Osaka T, Numba Y, Zimmet P, Inoue T. Criteria and classification of obesity in Japan and Asia-Oceania. Asia Pacific Journal of Clinical Nutrition. 2002;11(Suppl. 8):S732–S737
  21. Koeing W, Ernst E, Matrai A. Blood rheology associated with cardiovascular factors and chronic cardiovascular diseases. Results of an epidemiological cross-sectional study. Angiology. 1988;39:986–995
  22. Lowe G, Rumley A, Norrie J, Ford I, Shepherd J, Cobbe S, et al. Blood rheology, cardiovascular risk factors, and cardiovascular disease: the West of Scotland Coronary Prevention Study. Thrombosis and Haemostasis. 2000;84:553–558
  23. Lowik MR, Odink J, Kok FJ, Ockhuizen T. Hematocrit and cardiovascular risk factors among elderly men and women (Dutch Nutrition Surveillance System). Gerontology. 1992;38:205–213
  24. Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, et al. Subcutaneous adipose tissue release interleukin-6, but not tumor necrosis factor-alpha, in vivo. Journal of Clinical Endocrinology and Metabolism. 1997;82:4196–4200
  25. Nakanishi N, Suzuki K, Tatara K. White blood cell count and clustered features of metabolic syndrome in Japanese male office workers. Occupational Medicine. 2002;52:213–218
  26. Nieto FJ, Szaklo M, Folsom AR, Rock R, Mercuri M. Leukocyte count in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. American Journal of Epidemiology. 1992;136:527–537
  27. Pan, W. H., Flegal, K. M., Chang, H. Y., Yeh, W. T., Yeh, C. J., & Lee, W. C. (in press). BMI and obesity-related metabolic disorders between Taiwanese and US Whites and Blacks. American Journal of Clinical Nutrition.
  28. Park YW, Zhu S, Palaniappan L, Heshka S, Carnethon MR, Heymsfield SB. The metabolic syndrome: prevalence and associated risk factor findings in the US population from the third National Health and Nutritional Examination Survey, 1988–1994. Archives of Internal Medicine. 2003;163:427–436
  29. Pederson O, Beck-Nielsen H. A study of insulin receptors in human mononuclear leukocytes. Acta Endocrinology. 1976;83:556–564
  30. Perrine SP, Greene MF, Lee PDK, Cohen RA, Faller DV. Insulin stimulate core blood erythroid progenitor growth: evidence for an etiological role in neonatal polycythemia. British Journal of Hematology. 1986;64:503–511
  31. Pickup JC, Crook MA. Is type II diabetes a disease of the innate immune system?. Diabetologia. 1998;41:1241–1248
  32. Reaven GM. Role of insulin resistance in human disease. Diabetes. 1988;37:1595–1607
  33. Shimakawa T, Bild DE. Relationship between hemoglobin and cardiovascular risk factors in young adults. Journal of Clinical Epidemiology. 1993;46:1257–1266
  34. Sims E. In: Humoral factors. Oxford: IRL Press; 1993;p. 1–373
  35. Stefanini M, Urbas JV, Urbas JE. Gaisbock's syndrome: its hematologic, biochemical and hormone parameters. Angiology. 1978;29:520–533
  36. Targher G, Seidell JC, Tonoli M, Muggeo M, Sandre GD, Gigolini M. The white blood cell count: its relationship to plasma insulin and other cardiovascular risk factors in healthy male individuals. Journal of Internal Medicine. 1996;239:435–441
  37. Vinik AI, Erbas T, Park TS, Nolan R, Pittenger GL. Platelet dysfunction in type 2 diabetes. Diabetes Care. 2001;24:1476–1485

PII: S1056-8727(04)00003-0

doi: 10.1016/S1056-8727(04)00003-0

Journal of Diabetes and Its Complications
Volume 18, Issue 6 , Pages 322-327 , November 2004

Article Tools