Journal of Diabetes and Its Complications
Volume 19, Issue 1 , Pages 42-46 , January 2005

Total homocysteine levels relation with chronic complications of diabetes, body composition, and other cardiovascular risk factors in a population of patients with diabetes mellitus type 2

Received 5 June 2003 ,Revised 23 September 2003 ,Accepted 15 December 2003.

References 

  1. Arnesen E, Refsum H, Bonaa KH. Serum total homocysteine and coronary heart disease. International Journal of Epidemiology. 1995;24:704–709
  2. Boushey CJ, Beresford SAA, Omenn GS. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 1995;274:1049–1057
  3. Buysschaert M, Dramais AS, Wallemacq P, Hermans M. Hyperhomocysteinemia in type 2 diabetes. Diabetes Care. 2000;23:1816–1822
  4. Chico A, Perez A, Cordoba A, Arcelus R, Carreras G, de Leiva A, et al.  Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease?. Diabetologia. 1999;41:684–693
  5. Coldwell JA. Elevated plasma homocysteine and diabetic vascular disease. Editorial Diabetes Care. 1997;20:1805–1806
  6. Coull BM, Malinow MR, Beamer N. Elevated plasma homocystein concentration as a possible independent risk factor for stroke. Stroke. 1990;21:572–576
  7. Das S, Reynolds T, Patnaik A, Rais N, Fink LM, Fonseca VA. Plasma homocysteine concentrations in type II diabetic patients in India: Relationship to body weight. Journal of Diabetes Complications. 1999;13:200–203
  8. Fiorina P, Lanfredini M, Montanari A, Peca MG, Veronelli A, Mello A, et al.  Plasma homocysteine and folate are related to arterial boold pressure in type 2 diabetes mellitus. American Journal of Hypertension. 1998;11:1100–1107
  9. Foody JM, Milberg JA, Robinson K, Pearce GL, Jacobsen DW, Sprecher DL. Homcysteine and lipoprotein (a) interact to increase CAD risk in young men and women. Arteriosclerosis, Thrombosis and Vascular Biology. 2000;20:493–499
  10. Giles WH, Croft JB, Greenlund KJ, Ford ES, Kittner SJ. Association between total homocysteine and the likelihood for a history of acute myocardial infarctation by race and ethnicity: Results from the Third National Health and Nutrition Examination Survey. American Heart Journal. 2000;139:446–453
  11. Guttormsen AB, Ueland PM, Svarstad E, Refsum H. Kinetic basis of hyperhomocisteinemia in patients with endstage renal failure. Irish Journal of Medical Science. 1995;164:8
  12. Hoogeveen EK, Kostense PJ, Beks PJ. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: A population-based study. Arteriosclerosis, Thrombosis and Vascular Biology. 1998;18:133–138
  13. Jeger A, Kostense PJ, Nijpels G, Dekker JM, Heine RJ, Bouter LM, et al.  Serum homocysteine levels are associated with the development of microalbuminuria: The Hoorn stuy. Arteriosclerosis, Thrombosis and Vascular Biology. 2001;21:74–81
  14. Malinow MR, Nieto FJ, Szklo M. Carotid artery intimal-medial wall thickening and plasma homocystein in asymptomatic adults. The atherosclerosis Risk in Communities Study. Circulation. 1993;87:1107–1113
  15. Perry IJ, Refsum H, Morris RW. Prospective study of serum homocysteine concentration and risk of stroke in middle-aged British men. Lancet. 1995;346:1395–1398
  16. Pichard C, Slosman D, Hirschel B, Kyle U. Bioimpedance analysis in AIDS patients: An improved method for nutritional follow up. Clinical Research. 1997;41:53a
  17. Rosenberg IH, Miller JW. Nutrition factors in physical and cognitive functions of elderly people. American Journal of Clinical Nutrition. 1992;55:1237s–1243
  18. Selhub J, Jacques PF, Bostom AG. Association between plasma homocystein concentrationsand extracranial carotid-artery stenosis. New England Journal of Medicine. 1995;332:286–291
  19. Smulders YM, Rakic M, Slaats EH, Treskes M, Sijbrands EJ, Odekerken DA, et al.  Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria and cardiovascular disease. Diabetes Care. 1999;22:125–132
  20. Stabler SP, Estacio R, Jeffers BW, Cohen JA, Allen RH, Schrier RW. Total homocysteine is associated with nephropathy in non-insulin-dependent diabetes mellitus. Metabolism. 1999;48:1096–1101
  21. Stampfer MJ, Malinow R, Willett WC. A prospective study of plasma homocysteine and risk of myocardial infarctation US physicians. JAMA. 1992;268:877–881
  22. Tsai WC, Li YH, Tsai LM, Chao TH, Lin LJ, Chen TY, et al.  Correlation of homocysteine levels with the extent of coronary atherosclerosis in patients with low cardiovascular risk profiles. American Journal of Cardiology. 2000;85:49–52
  23. Verhoef P, Hennekens CH, Malinow MR. A prospective study of plasma homocysteine and risk of ischemic stroke. Stroke. 1994;25:1924–1930
  24. Weir D, Molloy A. Microvascular disease and dementia in the elderly: Are they related to hyperhomocysteinemia?. American Journal of Clinical Nutrition. 2000;71:859–860
  25. Welch G, Loscalzo J. Homocysteine and atherothrombosis (Review). New England Journal of Medicine. 1998;338:1042–1050

PII: S1056-8727(03)00116-8

doi: 10.1016/j.jdiacomp.2003.12.003

Journal of Diabetes and Its Complications
Volume 19, Issue 1 , Pages 42-46 , January 2005

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