Journal of Diabetes and Its Complications
Volume 17, Issue 1 , Pages 11-15 , January 2003

Association of monocyte chemoattractant protein-1 with renal tubular damage in diabetic nephropathy

  • Tsukasa Morii

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81-18-884-6040; fax: +81-18-884-6449
    • ,
  • Hiroki Fujita

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Takuma Narita

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Takashi Shimotomai

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Hiromi Fujishima

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Naomi Yoshioka

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Hirokazu Imai

      Affiliations

    • Department of Internal Medicine III, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Masafumi Kakei

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan
    • ,
  • Seiki Ito

      Affiliations

    • Department of Geriatric Medicine, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543 Japan

Received 16 August 2001 ,Revised 5 March 2002 ,Accepted 11 March 2002.

References 

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  7. Howard RL, Buddington B, Alfrey AC. Urinary albumin excretion, transferrin and iron excretion in diabetic patients. Kidney International. 1991;40:923–926
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  9. Kees-Folts D, Schreiner GF. A lipid chemotactic factor associated with proteinuria and interstitial nephritis induced by protein overload. Journal of the American Society of Nephrology. 1991;2:548
  10. Kunin CM, Chesney RW, Craig WA, England AC, DeAngelis C. Enzymuria as a marker of renal injury and disease: studies of N-acetyl-β-glucosaminidase in the general population and in patients with renal disease. Pediatrics. 1978;62:751–760
  11. Lloyd CM, Minto AW, Dorf ME, Proudfoot A, Wells TN, Salant DJ, et al. RANTES and MCP-1 play an important role in the inflammatory phase of crescentic nephritis but only MCP-1 is involved in crescent formation and interstitial fibrosis. Journal of Experimental Medicine. 1997;185:1371–1380
  12. Parving HH. Renoprotection in diabetes: genetic and non-genetic risk factors and treatment. Diabetologia. 1998;41:745–759
  13. Parving HH, Andersen AR, Smidt UM, Oxenboll B, Edsberg B, Christiansen JS. Diabetic nephropathy and arterial hypertension. Diabetologia. 1983;24:10–12
  14. Parving HH, Hommel E, Mathiesen E, Skott P, Edsberg B, Bahnsen M, et al. Prevalence of microalbuminuria, arterial hypertension, retinopathy and neuropathy in patients with insulin dependent diabetes. BMJ [British Medical Journal]. 1988;296:156–160
  15. Price RG. Measurement of N-acetyl-β-glucosaminidase and its isoenzymes in urine methods and clinical applications. European Journal of Clinical Chemistry and Clinical Biochemistry. 1992;30:693–705
  16. Prodjosudjadi W, Gerritsma JSJ, Klar-Mohamad N, Gerritsen AF, Bruijn JA, Daha MR, et al. Production and cytokine-mediated regulation of monocyte chemoattractant protein-1 by human proximal tubular epithelial cells. Kidney International. 1995;48:1477–1486
  17. Remuzzi G. Abnormal protein traffic through the glomerular barrier induces proximal tubular cell dysfunction and causes renal injury. Current Opinion in Nephrology and Hypertension. 1995;4:339–342
  18. Remuzzi G. Nephropathic nature of proteinuria. Current Opinion in Nephrology and Hypertension. 1999;8:655–663
  19. Remuzzi G, Ruggeneti P, Benigni A. Understanding the nature of renal disease progression. Kidney International. 1997;51:2–15
  20. Rovin BH, Yoshimura T, Tan L. Cytokine-induced production of monocyte chemoattractant protein-1 by cultured human mesangial cells. Journal of Immunology. 1992;148:2148–2153
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  22. Tarnow L, Rossing P, Gall MA, Nielsen FS, Parving HH. Prevalence of arterial hypertension in diabetic patients before and after the JNC-V. Diabetes Care. 1994;17:1247–1251
  23. Wada T, Furuichi K, Sakai N, Iwata Y, Yoshimoto K, Shimizu M, et al. Up-regulation of monocyte chemoattractant protein-1 in tubulointerstitial lesions of human diabetic nephropathy. Kidney International. 2000;58:1492–1499
  24. Wang Y, Chen J, Chen L, Tay Y-C, Rangan GK, Harris DCH. Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein. Journal of the American Society of Nephrology. 1997;8:1537–1545

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Journal of Diabetes and Its Complications
Volume 17, Issue 1 , Pages 11-15 , January 2003

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